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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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A Method of Machine Transliteration between Different Writing Systems
Published Monday, April 9, 2018BackgroundWriting system is a set of characters and the corresponding rules used to represent a language. Characters could be either graphemes (letters) or phonemes (characters representing a phonetic sound). The process of writing system conversion transforms one system into another using mapping rules. This could be accomplished either...
Categories: Information Technology
Keyword(s): 525
Docket: IS-2013-109
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Transformational Electronic Tool for Chemical Analysis: Oxidative Stress Detection
Published Tuesday, April 3, 2018Background Oxidative Stress is the long-term damage to DNA, RNA, lipids and proteins, in otherwise healthy biological cells, due to reactive oxygen species (RON), typically hydroxyl and peroxide ions among others. By damaging genetic information and other metabolic processes, oxidative stress can lead to a number of chronic conditions such as...
Keyword(s): 525
Docket: LS-2017-084
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Microtube platform for the thermal automation of multi-step reactions
Published Wednesday, March 28, 2018BackgroundThe automation of laboratory processes generally leads to increased quality control, higher throughput, and reduced operating costs. In fact, the global market for products related to laboratory automation, specifically liquid handling, is projected to be $ 3.5 billion in 2019 at an annual growth rate of 8.3%. Diagnostic assays...
Categories: Chemical, Microfluidics, Diagnostics
Keyword(s): 525
Docket: PS-2017-134
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Augmentarium
Published Monday, March 26, 2018Recent advances in sensor technologies have enabled the acquisition of very high resolution images that demand high-resolution displays. There has also been an increasing trend towards the generation and analysis of very high-fidelity time-varying datasets in scientific simulations. These simulations can range from several terabytes to a few...
Keyword(s): 525
Docket: IS-2015-005
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Generation of a Biomarker Kit with Prognostic Capability for Metastatic Breast Cancer
Published Monday, March 12, 2018Obscurins are a family of giant cytoskeletal proteins primarily localized at cell-cell junctions of breast epithelial cells. While abundantly expressed in healthy breast epithelial tissue, their expression is dramatically decreased in tissue from advanced stage breast cancer biopsies (grade 2 or higher) compared to matched normal samples....
Investigator(s): Aikaterini Kontrogiani-Konstantopoulos
Categories: Biomarker
Keyword(s): Diagnostics, Molecular biology, biomarker
Docket: AK-2016-131
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Simulated Electronic Health Record
Published Wednesday, February 28, 2018A large part of educating health professions students is preparing them for future practice. Much of today’s healthcare environment relies on technology, particularly an electronic health record (EHR). For the past several years, documentation during simulation events occurred through the use of paper charts, which is not consistent with current...
Categories: Software + Algorithm, Education/Training/Multimedia
Keyword(s): simulation, health
Docket: IS-2017-103
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Community-led Action in Response to Violent Extremism (CARVE) Training Course
Published Wednesday, February 28, 2018Community-led Action in Response to Violent Extremism (CARVE) is a 4-hour self-paced online course designed for a U.S.-based audience to provide community-focused, rigorously researched, and academically-informed instruction on Countering Violent Extremism (CVE). Targeted at the FEMA "awareness" training level, this FEMA-certified course is...
Categories: Software + Algorithm, Education/Training/Multimedia
Keyword(s): course, extremism, community
Docket: IS-2017-099
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REVEAL - Research-Enhanced Virtual Environment for Acquiring Language
Published Wednesday, February 28, 2018Researchers at the University of Maryland have created REVEAL (Research-Enhanced Virtual Environment for Acquiring Language), a method and associated system for providing an immersive 360-degree cinematic video language training experience to individuals learning a foreign language or receiving training or therapy in their first language. The...
Categories: Software + Algorithm
Keyword(s): virtual reality, language learning
Docket: IS-2017-091
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Risk-Based Path Optimization
Published Wednesday, February 28, 2018Operating unmanned aerial vehicles (UAVs) over inhabited areas requires mitigating the risk to persons on the ground. Because the risk depends upon the flight path, UAV operators need approaches that can find low-risk flight paths between the mission’s start and finish points. Since the flight paths with the lowest risk could be excessively long...
Categories: Software + Algorithm
Keyword(s): unmanned aerial vehicles, risk, reduction, mitigation, path optimization
Docket: IS-2017-064
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Global Terrorism Database
Published Wednesday, February 28, 2018The Global Terrorism Database (GTD) is an open-source database including information on terrorist events around the world from 1970 through 2017 (with additional annual updates planned for the future). Unlike many other event databases, the GTD includes...
Categories: Genomics/Proteomics/Database
Keyword(s): terrorism, national security, database
Docket: IS-2017-021