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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Method for Accelerating Nuclear Magnetic Resonance (NMR) Spectroscopy
Published Sunday, June 29, 2014BackgroundNuclear Magnetic Resonance (NMR) is used as the basis for NMR spectroscopy and Magnetic Resonance Imagining (MRI), which have applications in fields ranging from medical imaging to oil field exploration. To produce a useable spectra or image, a number of measurements must be taken over a period of time. In some fields, particularly...
Categories: Healthcare, Imaging devices
Keyword(s): NMR, MRI, Spectroscopy, imaging, Spectrometer
Docket: IS-2014-069
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Eventflow
Published Sunday, June 29, 2014EventFlow is an interactive visualization tool designed to facilitate analysis of temporal event sequences (as found in patient records, transaction logs, student records, incident...
Categories: Healthcare, Information Technology
Keyword(s): software, Data visualization, healthcare, healthcare records, data management, Electronic Health Records
Docket: IS-2014-062
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Low-Resistance Seamless Wedge Thermal Connectors
Published Thursday, June 19, 2014Low-Resistance Seamless Wedge Thermal Connectors Background Electronic equipment used in severe in environments such as military and aircraft applications cannot be adequately cooled down by the use of typical convection methods found inside most personal computers. Instead the equipment must rely on conduction cooling...
Categories: Microelectronics, Materials
Keyword(s): Heat Exchanger Enclosures, PCB, thermal conductivity
Docket: PS-2013-139
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Method for Morphological Analysis and an Error Tolerant Dictionary Lookup
Published Thursday, June 19, 2014BackgroundLanguage learners often wish to consult dictionaries to find the meaning of a newly encountered word. Imperfect recognition of the word (such as mishearings or misrecognition of letters) impedes this lookup. In addition, beginning language learners may not be able to transform a morphologically complex word into its canonical...
Categories: Education/Training/Multimedia, Information Technology
Keyword(s): language learning, pronunciation, phonetic, spelling
Docket: IS-2013-129
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Translation Memory Retrieval System
Published Thursday, June 19, 2014BackgroundTranslation memory systems containing a database of previously translated materials are widely used by translators. An important part of these systems is the matching algorithm that determines what translations get retrieved from the bank of available translations to assist the translator. A fundamentally important factor that...
Categories: Information Technology
Keyword(s): language tools, translate, TM, computer assisted translation
Docket: IS-2013-135
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Image Categorization System for Digital Forensics Applications
Published Wednesday, June 18, 2014Computerized image categorization systems are used to speed the identification and categorization of digital images. Categorizations for these systems are used in law enforcement and security where the systems can be used to identify missing people or identify a scene such as a terrorist training camp.Researchers at the University of...
Categories: Information Technology
Keyword(s): digital forensics image categorization automated security entertainment
Docket: IS-2008-064
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High Affinity Aptamer for Detection of HIV Reverse Transcriptase
Published Tuesday, June 3, 2014BackgroundThe development of multi-drug therapy for HIV has greatly extended the lives of patients undergoing multi-drug therapy. For best results, multi-drug therapy requires early detection and constant monitoring of viral loads in patients. Current technologies for viral load monitoring require dedicated machinery and highly skilled...
Categories: Research Tools, Antibodies, & Reagents
Keyword(s): HIV diagnostic, point-of-care
Docket: LS-2014-032
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Zona Incerta Stimulation for Chronic Pain Relief
Published Thursday, May 29, 2014Central pain syndrome (CPS) is a debilitating condition affecting with lesions or dysfunction in the central nervous system. CPS is a neurological disorder resulting from damage to or dysfunction of the pain-conducting pathways of the central nervous system. The patented invention describes a novel method for treating CPS regions of the...
Investigator(s): Asef Keller, Raimi Quiton, Peter Murray, Radi Masri, Jessica Lucas
Categories: Devices, Methods of Treatment
Keyword(s): chronic, pain, device, neurostimulation
Docket: AK-2009-044
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ZAP-70 As Biomarker and Immune System Modulator
Published Thursday, May 29, 2014The body's immune system is characterized by its ability to rapidly respond to foreign antigens (part of a bacterial or cancer cell, for example) that were previously encountered. This rapid response is mediated by memory T lymphocytes. When these cells are activated, they produce effector cytokines, such as TNF-alpha and IFN-gamma, which...
Investigator(s): Donna Farber, Francesca Okoye, Meena Chandok
Keyword(s): immune system, T cell, biomarker
Docket: DF-2008-006
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Vaccines Against ETEC with Isolation and Characterization of the csa Operon (ETEC-CS4 Pili)
Published Thursday, May 29, 2014Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in infants and young children in developing countries, accounting for a high rate of infantile morbidity and mortality, and is also a major cause of traveler's diarrhea. Following ingestion of contaminated food or water containing ETEC, the bacteria can attach to the small...
Investigator(s): Zeev Altboum, Myron Levine, Eileen Barry
Categories: Therapeutics, Vaccines
Keyword(s): vaccine, diarrheal
Docket: ZA-2000-053