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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Flapping Wing Insect-Inspired Micro Aerial Robotic Vehicle
Published Monday, October 12, 2015BackgroundMicro aerial vehicles (MAVs) at an insect scale would represent a phenomenal improvement in discrete reconnaissance vehicles. They would be especially advantageous for rapid exploration of small spaces and exploiting contextual camouflage. The ubiquitous occurrence of natural examples of insect-scale flapping flight suggests that...
Categories: Robotics, Robotics, Aerospace
Keyword(s): MAVs, Micro aerial vehicles, drones, Robotics
Docket: PS-2013-046
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Malware Detection with Download Graph Analytics
Published Monday, September 28, 2015BackgroundMalware detection on computers, tablets, smartphones, and other devices is a recurring issue in the software security field, as anti-malware vendors and malware developers use ever more complex techniques to identify and hide malware, respectively. Analysis of malicious executables can be difficult due to obfuscation, hiding, and...
Keyword(s): malware, cybersecurity, antivirus, software
Docket: IS-2015-122
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Event Category Matrix for Temporal Event Sequences
Published Monday, September 28, 2015BackgroundData analysts have encountered a consistent problem in starting their analyses due to visual complexities. The visual complexity of temporal event sequences in an aggregated view increases with the addition in the number of categories in the dataset. Some existing methods try to solve this problem by automatically simplifying the...
Keyword(s): 525
Docket: IS-2015-043
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System Health Management based on Hybrid Dynamic Bayesian Network Modeling
Published Monday, September 28, 2015BackgroundAs systems become more complex, there is a need to monitor different subsystems and components to detect failure. Even a relatively simple system, like a commercial UAV, can have dozens of sensors and components, each of which can be a point of failure. However, basic monitoring of these components is not enough, since failure may...
Keyword(s): reliability, engineering, safety, drones, autonomous systems
Docket: IS-2015-018
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Method for Image Reconstruction of Moving Radionuclide Source Distributions
Published Monday, September 28, 2015Positron emission tomography (PET) is a functional imaging technique for studying biological processes in vivo for pre-clinical and clinical studies. PET compounds labelled with short-lived positron emitters are delivered to a subject (human, animals or plants). The raw PET scanning data is reconstructed...
Investigator(s): Mark Smith
Categories: Imaging, Software + Algorithm, Other
Keyword(s): PET, SPECT, Image reconstruction, nuclear medicine
Docket: MS-2009-091
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Construction Method of Polar Codes
Published Sunday, September 27, 2015BackgroundPolar codes are a recently development type of linear block error correcting code that have several potential useful properties, including efficient encoding and decoding complexity, fully capacity achieving, and low error probabilities given sufficient block length. However, polar codes also have certain drawbacks, including high...
Keyword(s): Polar codes, error correction codes, ECC, Reed-Solomon, non binary, storage, communications systems
Docket: IS-2015-116
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Optimal Design of a Large Scale Microphone Network and Filtering System
Published Thursday, September 24, 2015BackgroundMicrophone arrays, a series of individual microphones operating in tandem for a given area, have a variety of uses including extracting specific sounds from an ambient environment, surround sound recording, and localization, among others. However, using a very large microphone array can be difficult. A very large array will generate...
Keyword(s): microphone arrays, sound segregation, multurate filterbanks
Docket: IS-2014-134
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Research Tool for Identification of Conditionally Enriched Protein Expression in Bacterial Cells
Published Tuesday, September 22, 2015BackgroundChanges in environmental conditions can drastically change the protein content of cells. The amount of specific proteins (i.e., their expression levels) can increase or decrease quickly in response to these environmental changes in order to insure cell survival. This rapid process happens at the translational and post-...
Categories: Research Tools, Antibodies, & Reagents
Keyword(s): 525
Docket: LS-2015-092
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Anti-shark IgNar mouse monoclonal (GA8) antibody
Published Tuesday, September 22, 2015The cartilaginous fish (sharks, skates, and rays) have a human-type adaptive immune system as well as immunoglobulins (Igs). In addition to the heavy-light chain heterodimeric isotypes (IgM and IgW), sharks also produce a novel isotype called IgNAR. IgNAR is a heavy chain homodimer that does not associate with light chains....
Investigator(s): Martin Flajnik
Categories: Research Tools, Antibodies, & Reagents
Docket: MF-2009-077
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A stable Receptor-Associated Protein (RAP) protein
Published Tuesday, September 22, 2015A novel Stable Receptor-Associated Protein (RAP), an antagonist of lipoprotein receptor-related protein 1 (LRP1). Dr. Strickland at UMB has developed a stable RAP D3 domain (with 6 mutations) that is resistant to both pH- and heat-induced denaturation. The molecule binds to lipoprotein receptor-related protein 1 (LRP1) with high affinity...
Investigator(s): Dudley Strickland
Categories: Research Tools, Antibodies, & Reagents
Keyword(s): RAP Protein stable
Docket: DS-2015-111