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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Method for Synthesizing Asymmetric Multi-Component Nanoparticles
Published Monday, May 27, 2013BackgroundMulticomponent nanoparticles represent an innovative approach to manufacturing new-generation composite materials with new, synergistic and improved properties that combine the desirable properties of the individual components. The attractive aspect of these hybrid multicomponent nanostructures is not only the combination of...
Categories: Nanotechnology + Nanoparticles + Nanomaterials
Keyword(s): imaging. theranostic, diagnostic, polymer, asymmetric nanoparticle, nanoparticle, Bioimaging Drug Delivery, Catalysis, Optoelectronic devices, Novel building blocks,new functional materials, functional devices, devices, material, nanomaterial, synthesis, nanoparticle, multi-component, 525
Docket: LS-2012-096
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One-pot Transformation Process for Making a Pure Provitamin a Carotenoid
Published Monday, May 27, 2013BackgroundCarotenoids are naturally occurring pigments present in fruits, vegetables, plants and in photosynthetic organisms like algae, bacteria and fungi. Carotenoids act as antioxidants that can potentially act against cancer, heart disease and can boost the immune system. Over 600 kinds of carotenoids have been isolated and...
Categories: Chemical
Keyword(s): carotenoid, beta-carotene, alpha-carotene, gamma-carotene, antioxidant, cryptoxanthin, zeaxanthin, nutrition, nutritional supplement, supplement, cancer, heart disease, macular degeneration, lutein
Docket: LS-2012-130
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Transistor Sensors for Detection of Chemicals and Biomolecules
Published Monday, May 27, 2013BackgroundNanotechnology offers opportunities in developing the ability to utilize the exceptional electrical properties of nanomaterials in complex chemical environments such as solar cells, fuel cells, microprocessors, and sensors. The challenge of creating a sensor nanomaterial that is not only highly sensitive to extremely low...
Categories: Nanotechnology + Nanoparticles + Nanomaterials
Keyword(s): CNT, SWCNT, carbon nanotube, Nanotube, nano, DWCNT, Double Walled Carbon Nanotube, thin film, Thin film transistor, thin film field effect transistor, covalent, sensor, functionalized CNT
Docket: PS-2013-009
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High Resolution, Real-Time Polling Application for Enhanced User Engagement
Published Wednesday, February 20, 2013BackgroundGathering and analyzing perceptions is a central problem in both research and industry, but existing methods have not yet met the challenge of today’s environment for collecting public opinion. Traditional survey-based polling is struggling with the challenge of reaching an increasingly large population who are unavailable or...
Categories: Education/Training/Multimedia
Keyword(s): REACTLabs, elections, polling, opinion gathering, real time reactions, app
Docket: IS-2012-074
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On-Board Electric/Hybrid-Electric Vehicle Universal Plug-in Charger with Active Power Filtering
Published Monday, February 11, 2013BackgroundOn-board battery charging power circuits will be commonplace in next generation vehicles, especially electric (EV), hybrid-electric (HEV), and fuel cell vehicles. These circuits can be external, isolated, or integrated with the battery and allow simple plug-in connections to the power grid for charging. Current battery charging...
Categories: Power Electronics
Keyword(s): capacitor efficient IEEE renewable alternative
Docket: PS-2012-116
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Method to Synthesize Stable, Self-Assembling Virus-like Nano Rods and Tubes
Published Wednesday, January 2, 2013BackgroundVirus-like nanoparticles (VLPs) are mere envelopes of viruses sans the genetic material that mimic the structure of actual viral particles. The expression of viral structural or capsid proteins can result in the self-assembly of these particles. In essence, they are non-infective virus-like particles that may be derived from...
Categories: Nanotechnology + Nanoparticles + Nanomaterials, Vaccines
Keyword(s): virus, virus-like nanoparticles, VLPs, TMV, Tobacco Mosaic Virus, electrode, vaccine, templating, biosensor, inorganic molecules, templating inorganic molecules, receptor, metallization, nano, nano-scale
Docket: LS-2012-093
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Material to Cheaply and Effectively Extract Uranium from Seawater
Published Wednesday, December 12, 2012BackgroundThe world’s oceans hold 1000 times more uranium than conventional ores. Unlike conventional mining, retrieving uranium from seawater requires no mechanical systems and has virtually no environmental impact. The feasibility of utilizing adsorbent fabrics for uranium extraction has already been proven by an extensive research effort...
Categories: Chemical, Materials
Keyword(s): yellow cake centrifuge depleted hazardous leech groundwater runoff pollution
Docket: PS-2012-086
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An Interferon Enhancer for Enhancement of Immune Response for Vaccine Applications
Published Wednesday, October 31, 2012BackgroundInterferons (IFNs) are a group of cytokines or proteins that are made and released by host cells in response to infections by viruses and bacteria. IFNs allow for host cells to communicate with each other and hence trigger a strong immune response. There are three types of IFNs that have similar functions of being antiviral and...
Categories: Vaccines, Biologics
Keyword(s): Interferon, IFN, viral, viral infection, bacterial, bacterial infection, infection, virus, bacteria, immune system, immune, immune response, pathogen, vaccine, cytokine
Docket: LS-2012-081
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A Tunable 2- and 3-Dimensional Cell Culture Substrate for the Isolation, Enrichment, and Study of Breast Cancer Stem Cells
Published Tuesday, October 30, 2012BackgroundThe cancer stem cell hypothesis argues that a small minority of cancer cells in a heterogeneous tumor population drives the tumor growth and is responsible for the relapse and metastasis of the disease. This minority cell population, referred to as cancer stem cells (CSC) due to its stem-cell-like characteristic, has drug-resistant...
Categories: Bioengineering
Keyword(s): diagnostic medical hospital screening PSA diagnosis
Docket: PS-2012-091
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Hybrid Polymer Hydrogels with Regions of Distinct Properties
Published Tuesday, October 30, 2012BackgroundPolymer hydrogels are three-dimensional networks of polymer chains cross-linked by chemical or physical bonds and swollen in water. Typical hydrogel formulations involve a monomer and crosslinker polymerized in water, and the properties of the resulting hydrogels can be tailored by altering the monomer or crosslinker formulation...
Categories: Biomaterials
Keyword(s): polymer contact lens lenses biomaterial skin wound artificial poly lactic acid
Docket: PS-2012-099