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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Atomic Layer Deposition for Metal Anode Passivation
Published Wednesday, November 11, 2015Background:Lithium metal is of great interest to the battery community: as the lightest and most electropositive alkali metal, Li has a low density, resulting in an extremely high specific capacity value of 3.86Ah/g and energy density of 11,701Wh/kg, making it the holy grail of battery anodes. Other light metals – Na, Mg, and Al – have...
Categories: Engineering, Power Electronics, Microelectronics
Keyword(s): Batteries, Lithium metal, Li-ion batteries, Energy storage, metal anode
Docket: PS-2014-155
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Multifunctional Energy Harvesting Skin
Published Tuesday, November 10, 2015Energy harvesting technologies currently enable wireless sensors to be operated without a battery but still require recharging or periodic replacement. Vibration is a widely available ambient energy source. Piezoelectric energy conversion from vibration is the most efficient approach known. A cantilever beam type generator is a popular device for...
Categories: Engineering, Power Electronics, Clean Technology
Keyword(s): 525
Docket: PS-2009-029
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Kidney Viability Assessment System
Published Monday, October 26, 2015Background:Kidney transplantation is a lifesaving therapy for patients with end-stage renal disease. Currently, over 100,000 patients are annually waiting for kidney transplants, with organ shortages posing a major problem in kidney transplantation. While the vast majority of kidneys used for transplantation are obtained from heart-...
Keyword(s): 525
Docket: PS-2013-151
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Graphene Oxide Water Separation Membranes for Water Purification
Published Monday, October 26, 2015Background:In recent years, nanomaterials have been extensively used in membrane synthesis and surface modification to improve membrane performance (e.g., flux, antibacterial property, fouling resistance, photocatalytic property) and to optimize the operation of membrane processes (e.g., energy consumption, maintenance requirement)...
Keyword(s): 525
Docket: PS-2013-125
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Safe, Low-Cost, High-Energy-Density, Solid-State Li-ion Batteries
Published Tuesday, October 20, 2015BackgroundThe adoption of the lithium-ion batteries in the consumer electronics, electric vehicle, and aerospace industries has grown exponentially over the years. Despite this growth, a call for a safer and more efficient rechargeable battery solution is at hand since lithium-ion batteries’ dangerous pressurized flammable liquid...
Categories: Devices, Engineering, Microelectronics, Power Electronics
Keyword(s): Soild-state, Lithium-ion, battery, 525
Docket: PS-2013-033
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Use of ELA peptide for treatment of cardiovascular disease and for improving fluid homeostasis
Published Tuesday, October 20, 2015Cardiovascular disease (CVD) continues to be one of America’s most serious and costly health issues. Though many therapeutic options exist to treat CVD, the majority of treatments address the symptoms of the disease and not the disease itself. This technology is a new class of therapeutic fusion proteins using the hormone Elabela (ELA) to...
Investigator(s): Da-Wei Gong (Lead PI)
Categories: Therapeutics, Biologics, Methods of Treatment
Keyword(s): MI, peptide, heart failure, myocardial infarction, cardiovascular, obesity, ELA, apelin
Docket: DG-2014-128
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Monoclonal antibodies to polycystin-1 protein
Published Monday, October 19, 2015Polycystin-1 (PC1) is a protein encoded by the Polycystic Kidney Disease 1 (PKD1) gene. It induces resistance to apoptosis and spontaneous proliferation of kidney tubular epithelial cells. Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disease that results in formation of fluid filled cysts in the kidney. As the...
Investigator(s): Feng Qian, Terry Watnick
Categories: Research Tools, Antibodies, & Reagents
Keyword(s): PKD, polycystic kidney disease polycystin-1
Docket: FQ-2015-089
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Antibacterial monomers, antibacterial resins and dental composites comprising the antibacterial resins
Published Thursday, October 15, 2015A major clinical problem associated with dental restorations is secondary cary formation and tooth restoration fractures. To address this issue, a new dental resin developed at the University of Maryland, Baltimore, was created that possesses superior mechanical strength and antimicrobial properties. The formulation...
Investigator(s): Huakun Xu, Michael Weir
Categories: Dental
Keyword(s): dental, cary, restorative, composite
Docket: HX-2013-023
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Motion Artifact Suppression in 4D CT Reconstruction with Iterative Back Projection
Published Thursday, October 15, 2015Computational tomography (CT) is computer-aided reconstruction imaging of X-ray projection data and is commonly used for diagnostic purposes. Although image quality is essential for diagnostic accuracy, CT images are prone to artifacts because the image is reconstructed using multiple measurements and a single error in...
Investigator(s): Byong Yong Yi, Nilesh Mistry, Cedric X Yu, Giovanni Lasio
Categories: Imaging devices, Software + Algorithm
Docket: BY-2014-089
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Fly-Ear Inspired Miniature Acoustic Sensor System
Published Monday, October 12, 2015Conventional directional microphones have various constraints when attempting to deliver high performance along with a small footprint. There is performance degradation when size decreases relative to the target sound wavelength. Thus, there is a need for a miniature microphone that is able to provide excellent sound source localization....
Categories: Sensors/Monitors, Microelectronics, Engineering, Devices
Keyword(s): 525
Docket: PS-2010-023