Search Technologies
Displaying 461 - 470 of 885 results
Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
Search by keyword:
-
A Microdevice for the Enrichment of Tumor-Initiating Breast Cancer Stem Cells
Published Wednesday, October 3, 2012BackgroundDespite the numerous advances in cancer treatment, there is frequent relapse and metastasis of cancer. The cancer stem cell hypothesis argues that a small minority of cancer stem cells (CSCs) in a heterogeneous tumor population drives the tumor growth and has drug resistant properties. One of the techniques in isolation and...
Keyword(s): 525
Docket: PS-2012-092
-
Vaccine Development using Functionalized Vesicles
Published Wednesday, October 3, 2012BackgroundOne of the greatest successes in public health in the last century has been the introduction of vaccines to prevent diseases. The mortality rate for many diseases, including smallpox, polio, diphtheria, and measles has been significantly reduced in the United States. However, the morbidity and mortality rates for some diseases...
Categories: Vaccines, Biomaterials
Keyword(s): Antigen screening, High-Throughput
Docket: LS-2012-060
-
Hybrid Plate Heat Exchanger
Published Wednesday, October 3, 2012Plate heat exchangers exhibit high performance as liquid to liquid heat exchangers. Their performance, however, is poor when fluid flow on different sides of the plates is much different than evaporators, for example. In that instance, the flow of evaporating fluid is significantly lower compared to a single phase fluid flow....
Categories: Industrial Processing
Keyword(s): heat exchanger, refrigeration, Thermal Energy Conversion
Docket: PS-2012-028
-
Capillary Fed Evaporator
Published Wednesday, October 3, 2012Most currently available evaporators are using boiling as the mechanism to remove heat from a surface by a working fluid. But this results in pressures that affect the efficiency of energy conversion processes, sometimes quite significantly. One such process is in Ocean Thermal Energy Conversion (OTEC), where the thermal cycle utilizes about 20°...
Categories: Industrial Processing
Keyword(s): Evaporators,Thermal Energy conversion, air conditioning
Docket: PS-2012-027
-
A Non-Intrusive Pressure-Line Dryer
Published Wednesday, October 3, 2012Although it is straightforward to use desiccant to dry the air that is confined inside a small container, it becomes challenging when the air pressure also needs to be constant and monitored. If a desiccant holder is attached to the system, then the total volume of the system is changed, which will impact the pressure measurement. In addition,...
Categories: Industrial Processing
Keyword(s): desiccant, humidity, Pressure-Line Dryer
Docket: PS-2012-025
-
Novel Pseudo-Peptides and Method of Synthesis with Applications in Bioremediation and Biotechnology
Published Wednesday, October 3, 2012BackgroundSynthetic biology enables researchers to design biologically active molecules that have wide-ranging applications in the pharmaceutical and chemical industries as a potential drug candidate or a precursor to creating other economically or biologically important compounds. Unnatural amino acids (UAAs) are chemically synthesized...
Categories: Biomaterials
Keyword(s): 525
Docket: LS-2012-022
-
Nano Arrays for Sensors
Published Wednesday, October 3, 2012Researchers at the University of Maryland’s Institute for Systems Research in the Department of Electrical and Computer Engineering have demonstrated the first utilization of virus molecules as a nano-scale bio-template assembled on an electrochemical sensor. The integration of versatile and inexpensive biological Tobacco Mosaic Virus (TMV) as a...
Categories: Nanotechnology + Nanoparticles + Nanomaterials
Keyword(s): Tobacco Mosaic Virus, nanotechnology, electrochemical
Docket: PS-2012-019
-
Ammonia Encapsulated in Hydrogels for Carbon Sequestration
Published Wednesday, October 3, 2012While great strides have been made towards the development of new technologies that will eventually alleviate our dependence on carbon-based energy, our environment is currently suffering the ill effects of increased carbon dioxide (CO2) in our atmosphere. Carbon sequestration, the process of removing carbon from the atmosphere through biological...
Categories: Chemical
Keyword(s): fertilizer, biodegradable hydrogel,
Docket: PS-2012-018
-
Fluorescent Porous Silica Nanoparticles for Drug Delivery, Diagnostic and Imaging Applications
Published Wednesday, October 3, 2012BackgroundThe majority of chemotherapeutic drugs are highly effective in eradicating cancer cells, however they act systemically and kill all cells with minimal selectivity based on cell type, resulting in high toxicity and serious side effects. Therefore, in traditional chemotherapy, the strength of cancer drugs that can be used is...
Categories: Nanotechnology + Nanoparticles + Nanomaterials, Imaging devices, Drug delivery devices
Keyword(s): targeted delivery, oncology
Docket: LS-2012-009
-
Highly Energy-Dissipative Ductile (HED) Diagrid Framing System
Published Wednesday, October 3, 2012High rise buildings in high seismic zones are susceptible to destructive high energy forces during major and even smaller earthquakes. Constructing buildings using a system that has both inelastic qualities for strength and elastic qualities to provide a measure of flexibility during seismic activity would undoubtedly be beneficial....
Categories: Engineering, Industrial Processing
Keyword(s): diagrid framing, high seismic zones, earthquake loading
Docket: PS-2011-114