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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Method of Using Fingerprint Patterns for Biometric Authentication
Published Thursday, October 30, 2014Biometrics involves measuring, analyzing, and using human physiological or behavioral traits to identify individuals with a high level of certainty. As such, it has the potential to certify the connection between people and the systems they are authorized to use. However, biometric data has a number of drawbacks. For example, it has a low level of...
Categories: Microelectronics, Information Technology
Keyword(s): biometrics, fingerprint, cryptography, authentication
Docket: IS-2009-023
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Domain Specific Test Design Automation
Published Thursday, October 30, 2014Today's software programs are becoming more and more complex - a fact which also makes them more error prone. Modern applications are written using functional programming - a single expression is used, which is executed by evaluating the expression. A spreadsheet is a good example of functional programming: in a spreadsheet, one can specify the...
Categories: Information Technology
Keyword(s): 525
Docket: IS-2003-085
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Extending and Maintaining Micropore Viability of Microneedle Treated Skin with Cholesterol Synthesis Inhibitors
Published Wednesday, October 1, 2014Transdermal drug delivery is an attractive alternative to oral delivery (which may reduce drug efficacy by first pass metabolism) and hyperdermic injections (which are commonly associated with pain and systemic side effects). A limited spectrum of drugs are able to passively cross the stratum corneum (SC, the outermost layer of...
Investigator(s): Audra L. Stinchcomb, Priyanka Ghosh
Keyword(s): Therapeutic
Docket: AS-2013-103
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An Automated Medical Student Performance Evaluation Software
Published Friday, September 26, 2014In the United States and Canada, a Medical Student Performance Evaluation (MSPE) is required as part of a medical student’s residency application. The MSPE includes specific information from the student’s academic record including both didactic and clinical courses. The Automated Student Affairs Processes (ASAP) is a user-friendly, platform...
Investigator(s): Kevin Brown, Priyanka Koneru, Sara Menso
Categories: Platforms, Software + Algorithm, Information Technology, Education/Training/Multimedia
Keyword(s): MSPE, software, medical school, administrative office, medical admissions
Docket: KB-2014-002
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Targeted Treatment for Methicillin-Resistant Staphylococcus aureus (MRSA) and Other Staph Infections
Published Tuesday, September 9, 2014BackgroundWhile the development of antibiotics is one factor that led to the increase in life expectancy in the United States, bacteria are beginning to develop resistance to antibiotics almost as quickly as new ones are developed. These bacteria seem to be developing resistance in health care facilities as most patients infected with...
Categories: Biologics
Keyword(s): MRSA, biofilm, anitbiotic resistant bacteria, enzymes
Docket: LS-2014-085
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TreeVersity: Visualizing Changes in Data Through Time With Dynamic Hierarchies
Published Tuesday, August 5, 2014BackgroundModern technology has provided a great increase in the amount and availability of information to analyze, making it easy for an user to become overwhelmed given a large dataset. Complex datasets may also have trends between two or more attributes that are not apparent when viewing the data in a traditional format like a table or...
Categories: Information Technology
Keyword(s): Data visualization
Docket: IS-2014-033
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Delivery of Therapeutics using Crystalized DNA
Published Thursday, July 31, 2014BackgroundAs therapeutics for disease become more specified, precise delivery of these treatments becomes more important. Recently, numerous new methods for the delivery of therapeutics have been developed and tested. Many of these methods involve encasing the therapeutic in a synthetic vesicle to protect and guide the treatment to its...
Categories: Biomaterials, Drug delivery devices
Keyword(s): natural products, DNA containers
Docket: LS-2014-084
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Stable Enzyme for the Prevention of Bacterial Biofilm Formation
Published Tuesday, July 29, 2014BackgroundAntibiotic-resistant bacteria are becoming a major health concern in the United States. While a major factor in the development of antibiotic resistance is due to the improper use of antibiotics, the formation of biofilms can also decrease the effectiveness of antibiotics. Biofilms form when free-moving bacteria undergo a...
Categories: Biologics
Keyword(s): biofilm, enzymes
Docket: LS-2014-087
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Method of Modifying Filtration Membranes
Published Wednesday, July 23, 2014Background:Polyethylene glycol (PEG) has been widely used and proven to be very efficient as an antifouling agent to reduce non-specific adsorption of proteins. Unfortunately, the chemical structure of PEG can be altered in the presence of oxygen and transition metal ions, thus damaging its ability to repel non-specific protein...
Categories: Materials
Keyword(s): Filtration, antifouling, Polyethylene glycol, membranes, biocompatibility,
Docket: PS-2013-126
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Simplified Synthesis of Polyubiquitin Chains
Published Sunday, July 20, 2014BackgroundUbiquitin is an important protein involved in the post-translational modification and trafficking of other cellular proteins. After attaching a single ubiquitin monomer to a protein, cells use the formation of polyubiquitin chains (attaching more ubiquitin to the initial monomer) to direct if the protein should be inserted into...
Categories: Research Tools, Antibodies, & Reagents
Keyword(s): Ubiquitin synthesis
Docket: LS-2014-029