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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Phylogeny Teaching Models
Published Sunday, March 11, 2012BackgroundPhylogenetics is the study of evolutionary relatedness among organisms and is one of the most important fields in evolutionary biology. It is a central component of undergraduate biology programs at colleges and universities as well as high school AP biology courses. However, phylogenetics is one of the most challenging...
Categories: Information Technology
Keyword(s): phylogeny, phylogenetic, evolution, evolutionary biology, teaching method, model, phylogeny model, evolutionary tree, educational product, education
Docket: IS-2011-110
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Compact Biomechanical Energy Harvester as a Battery Replacement
Published Tuesday, March 6, 2012Modern portable electronics rely exclusively on batteries for power. Obviously, batteries only have a limited duration before it is required to either recharge or replace them. For many users, recharging infrastructure is not readily available (nor the time necessary to fully recharge a battery) and carrying extra batteries is an incredible burden...
Categories: Bioengineering, Microelectronics
Keyword(s): high power density generator harvester lithium ion cathode anode electrolyte renewable long life
Docket: PS-2011-109
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Nanoengineered Chemical Sensors Offer Superior Detection of Environmental Pollutants, Hydrogen, and Other Industrial Chemicals
Published Sunday, March 4, 2012Detection of chemicals in air such as industrial pollutants, poisonous gases, chemical fumes, volatile organic compounds (VOCs), and trace explosives is vital for the health and safety of communities around the world; however, current methods of detection lack the sensitivity, selectivity, and cost benefits to be viable options. Techniques...
Categories: Sensors/Monitors, Chemical, Nanotechnology + Nanoparticles + Nanomaterials
Keyword(s): solid state sensor chemical vapor trace detection explosive dog sniffing
Docket: PS-2011-061
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Environmental Signatures for Forensic Analysis and Alignment of Media Recordings
Published Sunday, March 4, 2012In the modern era, a huge amount of digital information is available in the form of audio, image, video, and other sensor recordings. Stored on disks and other storage devices, this information has metadata describing the time and place of recording. However, digital tools can be used to modify the stored information. For example, digital...
Categories: Information Technology
Keyword(s): video surveillance, signal verification, location verification, anti tampering, security
Docket: IS-2011-090
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Data Communication Through Pipes and Structures By Dispersive Elastic Waves
Published Sunday, March 4, 2012BackgroundEmbedded sensors in large civil structures for structural health monitoring applications require data communication capabilities between sensor nodes. Conventional communication modalities include electromagnetic waves or acoustical waves. However, ultrasonic guided elastic waves that can propagate on solid structures such as pipes...
Categories: Sensors/Monitors
Keyword(s): structural health monitoring embedded sensor strain gauge corrosion
Docket: IS-2011-081
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Intracellular Neutralization Strategy Against the Influenza Virus and a Broad Spectrum of Pathogens
Published Wednesday, February 15, 2012BackgroundThe immune system is designed to generate a response and neutralize pathogens like bacteria and their toxins, viruses and other microorganism that invade the body tissues. It can be thought of a as a system that is distributed throughout the body in the form of immune cells and protein molecules like antibodies to defend the...
Categories: Vaccines, Biologics
Keyword(s): Vaccines,vaccine preparation and delivery,vaccine methods,antibody,antibody therapeutic,immunotherapy, immunotherapeutics,needle free,inhaled medication, Influenza, pathogen,Tuberculosis, Pneumonia, immunodeficiency, AIDS, sexually transmitted disorders,hepatitis,Chlamydia
Docket: LS-2011-101
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Application A: Novel Strategy to Regulate Inflammation; Application B: Novel Strategy to Facilitate Intracellular Delivery of Drugs Regardless of the Drug or Drug Carrier Geometry.
Published Wednesday, January 25, 2012For Application A: Novel Strategy to Regulate InflammationExecutive SummaryBackgroundInflammation involves migration of white blood cells or leukocytes from the circulation into tissues across a thin cell layer of cells (endothelial cells) that covers the inner wall of blood vessels. There are two recognized pathways...
Keyword(s): inflammation, cardiovascular disorders, inflammation regulation, intracellular drug delivery, drug delivery, acute lung injury, atherosclerosis, diabetes, hypertension, autoimmune diseases
Docket: LS-2010-107
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Human Exhaled Aerosol Droplet Biomarker System (HEAD Biomarker System)
Published Wednesday, January 25, 2012BackgroundChronic lung diseases have significant health and economic consequences worldwide. In 2011, the American Cancer Society estimates 221,130 new cases of lung cancer will be diagnosed in the U.S. and 156,940 deaths due to lung cancer (27% of all cancer deaths). It is estimated that approximately $10.3 billion is spent in the...
Categories: Biomarker
Keyword(s): Lung cancer, asthma, COPD, lung disease, Exhaled breath, breath condensate, breath, respiratory, respiratory illness, aerosol, biomarker, diagnostic, biomarker detection, non-invasive, drug therapy,non-invasive drug therapy
Docket: LS-2011-063
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Highly Concentrated Water Soluble Carbon Nanotube Ink
Published Wednesday, January 25, 2012BackgroundCarbon nanotubes are cylindrical nanostructured allotropes of carbon with unique properties. These carbon molecules have been extensively exploited for a variety of applications owing to their exceptional mechanical robustness, thermal conductivity, electronic transport and optical photoluminescence properties. One of its...
Categories: Nanotechnology + Nanoparticles + Nanomaterials
Keyword(s): carbon nanotube, Nanotube, Nanotube Ink, Ink, Nanoink, single-walled carbon nanotube, thermal conductivity, electronic transport, optical photoluminescence, dispersion
Docket: LS-2011-041
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Porous Monolith Sensing Elements for Molecular and Biomolecular Detection
Published Wednesday, August 17, 2011BackgroundIn flow-through immunoassays, capillaries and microfluidic channels have side walls upon which are anchored particular antibody probes chosen to capture specific antigens present in a fluid being measured. Antigen capture efficiency is limited by the surface areas of the sidewalls available for immobilizing the antibody probes...
Categories: Sensors/Monitors, Microfluidics
Keyword(s): immunoassay, porous, pores, surface area, microfluidic, SERS, polymer, monomer
Docket: PS-2010-029