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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Stimuli-Responsive Mesoporous Nanomaterials
Published Wednesday, April 29, 2009BackgroundCurrent chemotherapy treatments are effective in eradicating cancer cells, but the lack of tissue specificity severely limits the dosage that may be used to combat the disease. Traditionally, chemotherapy drugs have achieved selectivity by disabling processes that occur more frequently in cancer tissues than in healthy tissues. This...
Categories: Nanotechnology + Nanoparticles + Nanomaterials, Imaging devices
Keyword(s): chemotherapy, cancer, mesoporous particles, nanomaterials
Docket: LS-2008-025
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Efficient Key Exchange for Symmetric Cryptosystems
Published Sunday, April 26, 2009BackgroundThe efficient replacement of secret keys is a central problem of key management in symmetric cryptosystems. These systems are used to secure communications and electronic transactions between businesses, banks, and other entities where secure communications are required. In using such systems, messages between senders and receivers...
Categories: Information Technology
Keyword(s): security,cryptography,encryption,
Docket: IS-2008-112
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Method for Efficient Source Authentication for Multicast Communications in Hybrid Satellite/Wireless Networks
Published Monday, April 20, 2009Large wireless networks have the ability to provide rapid connectivity in disaster areas or military fields, or to inter-connect users in far-flung geographical locations. An addition of a satellite overlay to the wireless networks leads to a great improvement in the network performance. In the above hybrid wireless networks, security is a...
Categories: Microelectronics, Aerospace, Information Technology
Keyword(s): hybrid,satellite,communications,network,multicast,encryption,security,wireless
Docket: IS-2008-135
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Borrelia Burgdorferi Genetic Markers for Lyme Disease Diagnostics
Published Thursday, April 16, 2009BackgroundDiagnosing Lyme disease is notoriously difficult for physicians and veterinarians. Available tests have improved significantly over the last few decades but still leave much room for increased accuracy of results. As the genetic design of Lyme disease pathogen Borrelia burgdorferi is more fully understood, diagnostic kits may be...
Categories: Diagnostics, Biomarker
Keyword(s): Lyme Disease, Borrelia burgdorferi, B. burgdorferi, vaccine, diagnostic markers
Docket: LS-2009-015
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Natural Additives to Stabilize Food During Freeze-Thaw Cycles
Published Thursday, April 16, 2009Hydrocolloid Gum Mixture as Freeze-Thaw Stabilizer and Moisture Retainer Xanthan and Curdlan gums are food additives produced by microbial fermentation. They are widely used in the food industry to increase the quality of foods by stabilizing, thickening and emulsifying products such as ice cream, salad dressings and surimi. The...
Categories: Natural Compounds
Keyword(s): xanthan, curdlan, gum
Docket: LS-2008-018
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Synthesis Method for Curcumin
Published Wednesday, April 15, 2009Turmeric or "yellow root" is a general term for plants and plant materials having a high content of curcuminoids, compounds that have a strong coloring effect and which are used extensively in the coloring of e.g. food products. The term "curcuminoids" includes curcumin (C), reddish orange; demothoxy curcumin (DMC), orange-yellow and bis-...
Categories: Chemical, Natural Compounds
Keyword(s): Dietary supplement, natural extracts, health, food additives
Docket: LS-2006-046
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Lead-Free Antiferroelectric Compounds
Published Tuesday, April 14, 2009Solid solution PbZr1-xTixO3 in composition range 0...
Categories: Chemical, Materials, Microelectronics
Keyword(s): lead free antiferromagnetic compounds
Docket: PS-2007-015
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Post-Forming Extruded Profiles for Heat Transfer Applications Resulting in High Efficiency Cooling
Published Tuesday, April 14, 2009A majority of electronic devices are comprised of circuit boards with multiple heat generating chips of different height. Usually, machined high specification aluminum conduction plates or separate heat sinks are used for each chip. However, machined conduction plates are expensive and the use of separate heat sinks is complicated. Both have...
Categories: Materials, Engineering, Chemical, Devices
Keyword(s): extruded profiles heat transfer high efficiency cooling
Docket: PS-2007-058
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Modeling Facial Aging in Young Faces
Published Tuesday, April 14, 2009Researchers at the University of Maryland have been studying and developing personalized facial growth models based upon data gathered for an individual’s facial growth over a range of many years. More particularly, their work on these models for this current invention is for predicting an individual’s appearance by performing face recognition...
Categories: Information Technology, Software + Algorithm
Keyword(s): Modeling Facial Aging Young Faces
Docket: IS-2008-005
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A Rapid Method for Scanning Amino Acid Mutagenesis
Published Tuesday, April 14, 2009In order to study the relationship between structure and function of a protein, the DNA encoding the protein or its corresponding amino acid is subjected to mutations. A number of methods to mutagenize DNA have been developed including site-directed mutagenesis, linker scanning mutagenesis, and the alanine scanning mutagenesis. The first method...
Categories: Research Tools, Antibodies, & Reagents
Keyword(s): mutagenisis, mutation, DNA, amino acid, nucleotide, protein
Docket: LS-2007-026