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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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New Class of Antiepileptic Drugs
Published Monday, March 3, 2014BackgroundEpilepsy is a chronic neurological disorder characterized by recurrent seizures. These seizures are extremely debilitating and in some patients occur multiple times a day. Unfortunately, while numerous treatments for epilepsy have been developed, 25-30% of epilepsy patients do not achieve complete control of their seizures or...
Categories: Small molecules
Keyword(s): Epilepsy, Small Molecule Therapy
Docket: LS-2013-112
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NuMan Pro 5.3
Published Sunday, February 2, 2014The University of Maryland College of Agriculture and Natural Resources has released NuMan Pro 5.3, the most advanced software available to complete Maryland nutrient management plans. This software will work on computers supporting Windows 10 and 11. In addition to all of the features of NuMan Pro 5.2 (fertilizer recommendations for over 340...
Categories: Information Technology
Keyword(s): Nutrient Management, fertilizer, crop management, cropping management scenario
Docket: IS-2005-028
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Si-Carbon Nano-Tube (Si-CNT) Composites for Improved Lithium-ion Battery Electrodes
Published Monday, January 13, 2014BackgroundSilicon has been known as the highest capacity anode material to date for Li-ion batteries. However, during repeated lithiation and delithiation processes (charge-discharge cycles), significant swelling leads to anode fragmentation or pulverization, resulting in the loss of electrical connection. As a result, performance degradation...
Categories: Nanotechnology + Nanoparticles + Nanomaterials, Chemical
Keyword(s): battery power management cycle life extended
Docket: PS-2013-047
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Dynamic Proofs of Data Retrievability from Cloud Storage
Published Wednesday, December 4, 2013BackgroundData storage outsourcing has become one of the most popular applications of cloud computing, offering benefits such as economies of scale, flexible accessibility, efficiency, and allowing companies to focus on their primary business activities. Due to the increase in percentage of services conducted online and number of mobile...
Categories: Information Technology
Keyword(s): data big-data storage cloud security authenticity retrievability
Docket: IS-2013-096
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Enhanced Tuning of i-line Fabricated Optoelectronics for Greatly Increased Performance
Published Wednesday, November 13, 2013Backgroundi-line photolithography is a staple of modern microelectronics manufacturing, particularly optoelectronic devices such as laser diodes. As such, it is a very established and mature technology. However, microscale roughness is a known issue with i-line manufacturing, and devices manufactured with this method are ultimately...
Categories: Microelectronics
Keyword(s): semiconductor cmos lithography laser etch nano micro substrate epitaxial
Docket: PS-2013-085
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Creating Artificial Cell Membrane Using Biopolymers in Microfluidic Devices
Published Thursday, September 19, 2013BackgroundMembrane functionality in microfluidics enables sample separation, concentration, filtration, extraction, pumping, gradient generation, small molecule/cell communication, gas-liquid exchange, pressure measurement, and protein patterning. Of particular interest is the use of membrane structures to separate microfluidic chambers...
Categories: Microfluidics
Keyword(s): microfluidic, Membrane, polymer, biopolymer, chitosan, alginate, photolithography, biological, biological membrane, lab on a chip, biomembrane, permeable, permeability, process, detection kit, drug, drug permeability
Docket: LS-2013-078
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System to Assemble Influenza Virus and Other Pathogens Inside Host Cells for Vaccine Applications
Published Thursday, September 5, 2013BackgroundAccording to the CDC, “over a period of 30 years between 1976 and 2006, estimates of flu-associated deaths in the United States range from a low of about 3,000 to a high of about 49,000 people”. The unpredictable nature and severity of influenza viral infections necessitates the use of vaccines every season to receive...
Categories: Vaccines
Keyword(s): vaccine, flu, influenza virus, bacmid, Baculovirus, Live attenuated influenza virus, intranasal, flu vaccine,bacteria, virus, immune response
Docket: LS-2013-024
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Forward Imaging Doppler OCT Needle-type Probe for Real-time Image Guided Stereotactic Procedures
Published Monday, June 10, 2013BackgroundStereotactic procedures are those which require insertion of needle-based instruments into the brain. These neurosurgical procedures are employed for addressing a variety of medical conditions from biopsy of suspected tumors, to cell-based and gene therapy, to the placement of electrodes that are used for deep brain stimulation (DBS...
Categories: Imaging devices
Keyword(s): ultrasound nondestructive blood flow tissue laproscopic
Docket: PS-2012-126
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A Microbial Biosensor for Ethylene Gas
Published Monday, May 27, 2013BackgroundEthylene is a gas that serves as a hormone in plants and is critical for many aspects of plant growth and development such as stimulating or regulating the ripening of fruit, the opening of flowers, and the shedding of leaves. Environmental cues such as flooding, drought, chilling, wounding, and pathogen attack can induce...
Categories: Sensors/Monitors
Keyword(s): ethylene, gas, ethylene gas, gas detection, ethylene detection, detection, hormone, biosensor, sensor, ethylene receptor, receptor
Docket: LS-2012-090
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Self Assembling Inorganic Nanoparticle Vesicles - Building Blocks for Functional Nanomaterials
Published Monday, May 27, 2013Background-Self-assembly is the process by which the components of a preexisting disordered system spontaneously come together as an organized structure or pattern. The self-assembly of nanoparticles composed of two or more different materials into composite nanoparticles offers promising opportunities for synthesizing a variety of...
Categories: Nanotechnology + Nanoparticles + Nanomaterials, Research Tools, Antibodies, & Reagents
Keyword(s): vesicle, inorganic, inorganic material, imaging. theranostic, diagnostic, polymer, asymmetric nanoparticle, nanoparticle, Bioimaging, drug delivery, Catalysis, Optoelectronic devices, Novel building blocks,new functional materials, functional devices, devices, material, nanomaterial, synthesis, nanoparticle, multi-component, 525
Docket: LS-2012-097