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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Isolation of a Plant Promoter that Directs Gene Expression to the Root Cap and Can be Used to Target, to the Environment, Genes Beneficial for Plant Growth
Published Sunday, November 12, 2006This invention provides an AtCel5 gene promoter that is expressed exclusively in root cap cells of both primary and secondary roots of plants. AtCel5 is a soluble and secreted protein that plays a roll in sloughing of root cap cells from the root tip. Sloughing is critical because it assists the growing root in penetrating the soil. In...
Categories: Agricultural
Keyword(s): Plant Promoter, Gene Expression, Environmentally useful genes, Sloughing, Root Cap, Antibacterial proteins, Anti-Fungal proteins, Anti-nemotodal proteins.
Docket: LS-2005-045
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Method of Selectively Texturing Polycrystalline Fe-Ga Alloys to the <100> Orientation
Published Sunday, November 12, 2006Iron/gallium (Fe-Ga) alloys are known as a magnetostrictive alloy called Galfenol. Magnetostrictive materials are broadly defined as materials that undergo a change in shape due to change in the magnetization state of the material. Nearly all ferromagnetic materials exhibit a change in shape resulting from magnetization change. The percentage of...
Categories: Chemical
Keyword(s): Magnetostrictive materials, 525
Docket: PS-2004-117
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Novel Configuration of Thermoelectric Coolers to Cool High-Heat-Flux Hot Spots
Published Sunday, November 12, 2006Every effort that miniaturizes the integrated circuit (IC) comes with motivation for innovative on-chip thermal management systems. This is because smaller ICs have corresponding increases in transistor densities leading to corresponding increases in heat flux. Researchers at the University of Maryland have developed a thermal management...
Categories: Industrial Processing
Keyword(s): Thermal management, Integrated Circuit, Heat Flux
Docket: PS-2004-108
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Cell Sensor Based Pathogen Detection
Published Sunday, November 12, 2006A tremendous amount of research and development efforts are being dedicated to bio-chemical pathogen detection. Current commercially available pathogen detection systems have an unacceptably high rate of false positive results. This new technology will enable selective pathogen detection by exploiting the signaling machinery of living...
Categories: Bioengineering
Keyword(s): cell sensor, pathogen, detection, cell canary, MEMS, homeland security
Docket: PS-2004-083
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High Frequency Sampling SQUID Microscope
Published Sunday, November 12, 2006The current room temperature SQUID microscope has a bandwidth to a few hundred KHz. However, the bandwidth of the SQUID itself is much greater. The limitation has to do with bandwidth of the current electronics. This invention proposes electronics that will increase the bandwidth of the electronics to the GHz range.This is important...
Categories: Nanotechnology + Nanoparticles + Nanomaterials, Imaging devices
Keyword(s): Superconducting Quantum Interference Device, 525
Docket: PS-2004-026
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Eukaryotic Heme Transport as a Drug Target for Helminthic Infections
Published Sunday, November 12, 2006Helminthic infestations by parasitic worms afflict more than two billion people worldwide and cause more than eighty billion dollars of annual crop-loss globally. Novel treatments for these parasitic infections, for which there is no universal cure, can be developed based on studies by a University of Maryland researcher on heme transport using...
Categories: Natural Compounds, Drug Screen
Keyword(s): heme, heme synthesis, iron deficiency, anemia, parasite, parasitic infections
Docket: LS-2004-002
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Video Frame Ranking Toolbox (VFRT)
Published Sunday, November 12, 2006This code improves the performance of the Video Frame Ranking Toolbox. A set of software modules for ranking all frames of a video sequence according to a relevance linked to activity in the video. The purpose of this toolbox is to help developers speed up the implementation of application requiring the selection of a variable percentage of...
Categories: Information Technology
Keyword(s): video editing, fast-forward
Docket: IS-2003-083
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Hierarchical Clustering Explorer (HCE)
Published Sunday, November 12, 2006Multidimensional data sets are common in many research areas, including microarray experiment data sets. Genome researchers are using cluster analysis to find meaningful groups in microarray data. Some clustering algorithms, such as k-means, require users to specify the number of clusters as an input, but users rarely know the right number...
Categories: Information Technology
Keyword(s): Multidimensional data sets, clusters, 525
Docket: IS-2003-068
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Key-Management Scheme and Apparatus for Distributed Sensor Networks
Published Sunday, November 12, 2006The increased utilization of Distributed Sensor Networks (DSNs), for security and military purposes, poses a huge challenge in providing such networks with strong security measures in terms of confidentiality, authentication, data integrity, key distribution, and network administration. On the other hand, the typical constraints for power...
Categories: Microelectronics, Information Technology
Keyword(s): distributed sensor networks, digital, ad-hoc networks, key management, security software, DSN, homeland security
Docket: IS-2003-065
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Tailor-made Synthesis of Cucurbit[n]uril Analogs: Bis(phythalhydrazides) as Glycouril Surrogates
Published Sunday, November 12, 2006The similarity between the molecular shape of cyclic hexameric compound known as CB[6] and the shape of a pumpkin provided the impetus for Mock and co-workers to name this molecule a cucurbituril. Through their pioneering work, the groups of Mock and Kim have defined the molecular recognition properties of CB[6] and demonstrated its application in...
Categories: Drug delivery devices
Keyword(s): cyclo dextrines, sensor, catalyst, cucurbit, organic compound
Docket: LS-2003-005