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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Molecular Container to Enhance Solubility of Drugs
Published Tuesday, May 25, 2010BackgroundOne of the key obstacles encountered by the pharmaceutical industry is the deficient bioavailability of drugs due to poor aqueous solubility. One approach to address this problem is the development of molecular containers that encapsulate and thereby solubilize otherwise insoluble drugs in an aqueous environment. Ideally, such...
Categories: Drug delivery devices
Keyword(s): Curcubit[n] type containers, Cyclodextrins, drug delivery, Aqueous Solubility for Drugs and Pharmaceutical agents
Docket: LS-2010-039
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A Novel Discretely Actuated and Steerable Probe for Percutaneous Procedures
Published Monday, May 24, 2010BackgroundIn diagnostic and therapeutic medical procedures such as biopsy and radiofrequency ablation, a needle is used to reach a predetermined target. When flexible, bevel-tipped needles are inserted into soft tissue, they bend due to tip asymmetry, often resulting in targeting errors. Innovative TechnologyTo improve steering...
Categories: Imaging devices, Imaging
Keyword(s): needle, cannula, probe, biopsy, tissue, target
Docket: PS-2010-048
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TwitterStand: A Dynamic Aggregator for New Media
Published Tuesday, March 30, 2010Researchers at the University of Maryland have built a spontaneous news medium for news generation and collection with the idea of bypassing the traditional setup of reporters and newspapers. The system, called TwitterStand, uses messages (i.e., Tweets) posted in Twitter to automatically obtain breaking news. The key novelty behind TwitterStand is...
Categories: Information Technology
Keyword(s): twitter, aggregator, software
Docket: IS-2009-116
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Video Precis
Published Tuesday, March 30, 2010BackgroundIn video surveillance and web-based browsing, enormous amounts of data are received and stored. Processing this data for its information content relevant to a particular application can become quite cumbersome to the point that the data is rendered mostly useless. Innovative TechnologyUniversity of Maryland...
Categories: Education/Training/Multimedia, Information Technology
Keyword(s): surveillance, video, browsing
Docket: IS-2009-105
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Nano Arrays For Energy Storage
Published Tuesday, March 30, 2010BackgroundFabricating next generation nano-structured devices using densely packed interfaces and thin films is highly desirable in markets searching for high density energy storage, particularly with high power capability. Current high density storage systems are relatively high in per unit, installation, and maintenance costs, and are not...
Categories: Microelectronics, Nanotechnology + Nanoparticles + Nanomaterials, Power Electronics, Materials
Keyword(s): energy, nano, capacitor, array
Docket: PS-2009-094
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Multi-Pitch Tracking in Adverse Environments
Published Tuesday, March 30, 2010BackgroundThe field of speech processing includes techniques for enhancing speech in conversations and music. Researchers have made recent improvements in separating speakers of interest from their noisy backgrounds. Since many conversations take place in loud environments that include background noise, interfering speakers, etc., relevant...
Categories: Information Technology
Keyword(s): speech, algorithm, tele
Docket: IS-2009-044
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Molecular Container that aids in Recovery from Anesthesia
Published Monday, March 8, 2010BackgroundRocuronium is a neuromuscular blocking agent commonly used as general anesthetic during surgery. It is desirable to be able to reverse the effects of rocuronium following surgery for reduced side effects and quick patient recovery. One method to achieve this reversal is the introduction of a molecular container compound capable of...
Categories: Drug delivery devices, Nanotechnology + Nanoparticles + Nanomaterials
Keyword(s): rocuronium, anesthesia, container, cucurbituril, cucurbit[n]uril
Docket: LS-2010-001
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Nanolithography with Nanowire Arrays
Published Thursday, January 7, 2010BackgroundIntegrated circuits are used in nearly all electronic equipment currently in production. Also known as microchips, they control everything from computers to cell phones to microwave ovens. The performance of these chips depends on features that are only a few tens of nanometers across and that can be assembled in extremely close...
Categories: Nanotechnology + Nanoparticles + Nanomaterials, Industrial Processing, Engineering, Materials
Keyword(s): circuits, photon, nano, computer, chip
Docket: LS-2009-123
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Method to Prepare Sulfated Psyllium for Use to Reduce the Risk of Chronic Human Diseases
Published Thursday, January 7, 2010Psyllium, the seed husk of the plant genus Plantago, is an excellent source of soluble and insoluble dietary fibers. Its nutritional properties have the potential to be harnessed for important medical benefits, including the treatment of constipation, heart disease, colon cancer, gastric hypoacidity, and obesity. Unfortunately, psyllium’s...
Keyword(s): psyllium, nutrition, heart disease, dietary fiber
Docket: LS-2009-086
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World Gas Model
Published Thursday, January 7, 2010The World Gas Model, developed at the University of Maryland, offers an in-depth, interactive model of global natural gas markets unmatched in scope and depth of information. Features of the software include- coverage of 95% of worldwide natural gas production- inclusion of 73 production and 75 consumption countries- use of...
Categories: Software + Algorithm
Keyword(s): model, gas, natural gas, energy, market, game theory
Docket: IS-2009-045